Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Mayo Clinic
Study ID
NCT05410977
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Biospecimen Collection — PROCEDURE
    Undergo collection of blood and stool samples
  • Electronic Health Record Review — OTHER
    Medical records reviewed

Study Details

This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening technique for the detection of colorectal cancer in Lynch syndrome patients.

Key Dates

Start date
Mar 30, 2022
Status verified
May 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
950 participants (estimated)

Arms

  • Arm: Observational (biospecimen collection, record review)
    Patients undergo collection of blood and stool samples no more than 90 days prior to or between 7-90 days after standard of care colonoscopy or flexible sigmoidoscopy. Patients' medical records are also reviewed.

Primary Outcome Measure

Sensitivity of multitarget stool deoxyribonucleic acid (mt-sDNA) 2.0 test to detect colorectal neoplasia [ Time Frame: Up to 4 years ]

Central Contacts

Locations (9)

FacilityCityStateZIPSite coordinators
Mayo Clinic in ArizonaScottsdaleArizona85259
Colleen Gallagher
[email protected]
480-574-1346
Clinical Trials Referral Office
[email protected]
855-776-0015
Jewel Samadder, M.D. (PRINCIPAL_INVESTIGATOR)
University of California San FranciscoSan FranciscoCalifornia94115
Rachael Leigh Delacruz
[email protected]
415-514-8087
Aparajita Singh,, MD (PRINCIPAL_INVESTIGATOR)
University of Colorado Anschutz Medical CenterAuroraColorado80045
Mahlet Haileyesus
[email protected]
303-724-6070
Swati Patel, MD (PRINCIPAL_INVESTIGATOR)
Mayo Clinic in FloridaJacksonvilleFlorida32224
Clinical Trials Referral Office
[email protected]
855-776-0015
Douglas L. Riegert-Johnson, MD (PRINCIPAL_INVESTIGATOR)
Beth Israel Deaconess Medical CenterBostonMassachusetts02215
Katharine Germansky, MD
[email protected]
617-667-5661
Katharine Germansky, MD (PRINCIPAL_INVESTIGATOR)
Dana Farber Cancer InstituteBostonMassachusetts02215
Rachel Yore
[email protected]
857-215-2924
Sapna Syngal, MD, MPH (PRINCIPAL_INVESTIGATOR)
Mayo ClinicRochesterMinnesota55905
Rosalie Himle
[email protected]
507-266-5755
Clinical Trials Referral Office
[email protected]
855-776-0015
John Kisiel, M.D. (PRINCIPAL_INVESTIGATOR)
University of PennsylvaniaPhiladelphiaPennsylvania19104
Michaela Dungan
[email protected]
215-360-0833
Bryson Katona, MD, PhD (PRINCIPAL_INVESTIGATOR)
University of WashingtonSeattleWashington98102
Brian Foerster
[email protected]
206-685-1179
William Grady, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Scottsdale, AZ

By condition
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By specialty
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Mayo Clinic in Arizona· Scottsdale, AZUniversity of California San Francisco· San Francisco, CAUniversity of Colorado Anschutz Medical Center· Aurora, COMayo Clinic in Florida· Jacksonville, FLBeth Israel Deaconess Medical Center· Boston, MADana Farber Cancer Institute· Boston, MA

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