Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Melissa Pugliano-Mauro
Study ID
NCT05408117
Status
Recruiting
Apply to this trial

Conditions

  • Scar

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • 5-0 Polypropylene epidermal suture — DEVICE
    Split-wound, intra-individual comparison - half of wound will receive 5-0 polypropylene epidermal suture and half of wound will receive 5-0 fast gut epidermal suture
  • 5-0 Fast gut epidermal suture — DEVICE
    Split-wound, intra-individual comparison - half of wound will receive 5-0 polypropylene epidermal suture and half of wound will receive 5-0 fast gut epidermal suture

Study Details

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.

Key Dates

Start date
Oct 1, 2022
Status verified
Jun 2026
Primary completion
Aug 29, 2027
Completion
Oct 1, 2027

Study Design

Enrollment
34 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: A= left/superior half of wound
    Patients with skin of color undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater
  • Experimental: B= right/inferior half of wound
    Patients with skin of color undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater

Primary Outcome Measure

POSAS [ Time Frame: Suture removal date which is 7 days from the procedure if the excision is on the head or neck and 10 days from the procedure if the excision is on the trunk or extremities ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
UPMC PresbyterianPittsburghPennsylvania15213
Melissa Pugliano-Mauro, MD
UPMC Shadyside PlacePittsburghPennsylvania15232
Melissa Pugliano-Mauro, MD
UPMC St. MargaretPittsburghPennsylvania15215
Melissa Pugliano-Mauro, MD

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By research site
UPMC Presbyterian· Pittsburgh, PAUPMC Shadyside Place· Pittsburgh, PAUPMC St. Margaret· Pittsburgh, PA

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