Building Resilient Families

Conditions

• Adverse Childhood Experiences

Eligibility Criteria

Sex

ALL

Age

3 Years - 11 Years

Healthy Volunteers

Accepted

Interventions

• Three-Tier Model — BEHAVIORAL
  Families in the intervention will be counseled by a pediatric provider about ACEs, resilience, stress management, and healthy relationships. Families will also be referred to community health workers and parenting educators.

Study Details

Prior research suggests that it is possible to improve health outcomes in children with ACEs through multi-component interventions. The challenge for most communities is that health and education systems are fragmented and fail to accommodate families based upon different levels of need. This study utilizes cross-sectoral partnerships to mobilize three vectors (pediatricians, community health workers and parenting educators) to optimize the delivery of vital information and resources to a diverse population of families with ACEs. All vectors are trained in an evidence-informed curriculum to strengthen families and build youth resilience. The study design is a randomized controlled trial of 340 families of children between the ages of 3 to 11 who are generally healthy and have recently seen a pediatrician for a well-child visit. To evaluate the efficacy of this intervention, pediatric patients are invited to participate in repeat evaluations within 2 weeks, 3 months, 6 months, and 12 months after their well-child visit. The study will evaluate the following: 1) the association between Child-ACE scores and biomarkers of toxic stress at baseline in children age 3-11 years old; 2) whether the intervention reduces toxic stress and child health and psychosocial problems at follow-up for children with ACEs compared to usual well-child care for children with ACEs; and 3) the impact of mediating and moderating variables. These results will demonstrate that for families with ACEs the intervention will decrease toxic stress associated with ACEs, improve health outcomes, and reduce health disparities.

Key Dates

Start date

May 24, 2022

Status verified

Jun 2026

Primary completion

May 31, 2027

Completion

May 31, 2028

Study Design

Enrollment

340 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Arms

• Experimental: Three-Tier Model
  130 children with ACEs who received well-child care by a trained provider will be enrolled in this group.
• No Intervention: Comparison Group
  80 children without ACEs who received usual well-child care will be enrolled in this group.
• No Intervention: Control Group
  130 children with ACEs who received usual well-child care will be enrolled in this group.

Primary Outcome Measure

Child Allostatic Load Index [ Time Frame: Change between baseline and visit 4 (1-year post-enrollment) ]

Central Contacts

• Ariane Marie-Mitchell, MD, PhD, MPH
  909-651-5672
  [email protected]

Locations (1)

Find similar trials in Loma Linda, CA

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