A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT05357690
Phase
PHASE2/PHASE3
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Stellate ganglion block — PROCEDURE
    Ultrasound guided injection into the stellate ganglion performed in the right side of the neck in a sterile fashion.
  • Bupivacaine — DRUG
    10 mL of 0.5% without epinephrine injected in the plane of the right stellate ganglion
  • Placebo — DRUG
    10 mL of saline injected in the plane of the right stellate ganglion

Study Details

The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.

Key Dates

Start date
Apr 19, 2023
Status verified
May 2026
Primary completion
Jul 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
220 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Stellate ganglion block with local anesthetic
    Subjects will receive a single injection of bupivacaine in a stellate ganglion block
  • Sham Comparator: Stellate ganglion block with saline placebo
    Subjects will receive a single injection of saline in a stellate ganglion block

Primary Outcome Measure

Incidence of atrial fibrillation [ Time Frame: Within one week of surgery or during hospitalization if discharged prior to one week ]

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Erica Wittwer, MD
[email protected]
507-255-9814

Find similar trials in Rochester, MN

By condition
Atrial fibrillation
By specialty
CardiologyHeart disease
By research site
Mayo Clinic in Rochester· Rochester, MN

Related Studies