Engage for Late-Life Depression and Comorbid Executive Dysfunction

Part of paid clinical trials in Las Vegas, Nevada.

Sponsor
University of Nevada, Las Vegas
Study ID
NCT05356611
Status
Recruiting

Conditions

  • Depression in Old Age
  • Executive Dysfunction
  • Mild Cognitive Impairment
  • Psychotherapy

Eligibility Criteria

Sex
ALL
Age
60 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Engage — BEHAVIORAL
    Engage is a 9-week, behavioral-based, psychotherapy treatment protocol for late-life depression.

Study Details

Although there are an increasing number of mental health treatment adaptations for older adults, there are still a number of factors to consider when making these adaptations. Cognitive decline is one such factor that places significant burden on older adults and can interfere with traditional mental health therapies. Engage is a behavioral treatment approach that has shown to be effective in treating late life depression. The investigators are testing the feasibility of Engage as a treatment method for late life depression in older adults with cognitive decline. The objective is to corroborate Engage as an alternative late life depression treatment method for a sub-population of older adults with cognitive decline. Cognitive decline poses a unique mental health treatment barrier that is often over looked in younger populations. With a relatively higher prevalence of cognitive decline in older adulthood, it is imperative that a feasible mental health treatment program that can be effective in the presence of cognitive decline.

Key Dates

Start date
Sep 24, 2023
Status verified
Aug 2024
Primary completion
Dec 31, 2024
Completion
May 31, 2025

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Engage Treatment
    The study is a single-arm study. The single-arm will be implementation of the 9-week protocol of Engage in an older adult population with late-life depression and comorbid executive dysfunction and mild cognitive impairment.

Primary Outcome Measure

Hamilton Depression Rating Scale [ Time Frame: Assessed at Baseline, Week 6, Week 9, and Week 36 follow-up. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of NevadaLas VegasNevada89154
Brenna R Renn, PhD
702-895-0596
Matthew S Schurr, MA (SUB_INVESTIGATOR)

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