Vitamin A Status in Patients With Vocal Fold Leukoplakia

Part of paid clinical trials in Madison, Wisconsin.

Sponsor
University of Wisconsin, Madison
Study ID
NCT05323292
Status
Enrolling By Invitation

Conditions

  • Leukoplakia
  • Vitamin A
  • Vitamin A Deficiency
  • Vocal Cord Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

This study will determine systemic vitamin A status and lesion histopathology of participants with vocal fold hyperkeratosis resulting in clinical leukoplakia.

Key Dates

Start date
Jun 29, 2022
Status verified
Dec 2025
Primary completion
Jun 30, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Leukoplakia due to hyperkeratosis with dysplasia
    Biopsy-confirmed diagnosis of hyperkeratosis with dysplasia.
  • Arm: Leukoplakia due to hyperkeratosis with no dysplasia
    Biopsy-confirmed diagnosis of hyperkeratosis with no dysplasia.
  • Arm: Control group
    Laryngoscopy showing no evidence of vocal fold epithelial disease.

Primary Outcome Measure

Vitamin A liver reserves [ Time Frame: 14 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Wisconsin Hospitals and ClinicsMadisonWisconsin53792-

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