THC Effects on Glucose in Type 2 Diabetes

Part of paid clinical trials in La Jolla, California.

Sponsor
University of California, San Diego
Study ID
NCT05322213
Phase
PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
21 Years - 70 Years
Healthy Volunteers
Not accepted

Interventions

  • THC — DRUG
    2-Week, once daily, flexible dose, inhaled THC
  • Placebo — DRUG
    2-Week, once daily, flexible dose, inhaled placebo

Study Details

This study will examine the effects THC has on Glucose Metabolism and Endothelial Functioning in participants with Type 2 Diabetes. The participants will complete blood tests and tests to measure energy expenditure, CVD risks, and glucose metabolism. These tests will be performed prior to start of treatment and again after 2-weeks of treatment with the THC or placebo.

Key Dates

Start date
Aug 22, 2024
Status verified
May 2025
Primary completion
Dec 31, 2027
Completion
Jun 30, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Active THC
    Daily, inhaled, flexible dose of cannabis product with THC.
  • Placebo Comparator: Placebo Cannabis
    Daily, inhaled, flexible dose of cannabis product without THC.

Primary Outcome Measure

Change in Glucose Uptake [ Time Frame: 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UC San Diego Altman Clinical & Translational Research InstituteLa JollaCalifornia92037
Todd May, MS
[email protected]
Jeremy Pettus, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in La Jolla, CA

By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
UC San Diego Altman Clinical & Translational Research Institute· La Jolla, CA

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