Aromatherapy Inhaler Use for HSCT Distress

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT05302583
Status
Recruiting
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Conditions

  • Aromatherapy
  • Cancer Coping
  • Cancer Distress
  • Hematopoetic Stem Cell Transplant

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Aromatherapy Stick — OTHER
    Participants receive aromatherapy inhaler education and an aromatherapy stick for self-administered inhalation during the early post-transplant inpatient period. Aromatherapy use occurs on the assigned Inhaler Use Day (targeted for Transplant Day +1, +2, or +3) and is documented using an inhaler use log. Total exposure is limited to a maximum of 2 hours.
  • Standard of Care — OTHER
    Participants receive standard inpatient supportive care during the acute post-HCT period. No aromatherapy inhaler is provided.

Study Details

This randomized controlled trial will evaluate the feasibility and acceptability of an inhaled aromatherapy stick for patients during the acute inpatient phase after hematopoietic cell transplantation (HCT) . The study will also explore whether aromatherapy use is associated with short-term changes in patient-reported cancer-related distress and coping self-efficacy.

Key Dates

Start date
Jun 16, 2025
Status verified
May 2026
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Active Comparator: Usual Care
    Participants receive standard supportive care during hospitalization. No aromatherapy stick is provided.
  • Experimental: Aromatherapy + Usual Care
    Participants receive standard supportive care plus aromatherapy inhaler education and an aromatherapy stick for self-administered inhalation. Aromatherapy use occurs on the assigned Inhaler Use Day (targeted for Transplant Day +1, +2, or +3). Use is tracked with an inhaler use log. The aromatherapy "dose" is standardized by a maximum total exposure time (up to 2 hours total), while allowing participants to choose how to distribute use.

Primary Outcome Measure

Change in cancer distress (NCCN Distress Thermometer) [ Time Frame: Baseline: SOC/Inhaler Use Day (Transplant Day +1, +2, or +3); Follow-up: Study Completion Day (Transplant Day +2, +3, or +4) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford UniversityStanfordCalifornia94305
Anna Oh, PhD, MPH, RN
[email protected]
650-512-6691
Anna Oh, PhD, MPH, RN (PRINCIPAL_INVESTIGATOR)

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