Sickle Cell Disease (SCD) Bone Pain Study

Part of paid clinical trials in Sacramento, California.

Sponsor
University of California, Davis
Study ID
NCT05283148
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Dual-energy X-ray absorptiometry — OTHER
    Measure bone mineral density at the lumbar spine, left total hip, left forearm, and whole body
  • Vertebral fracture analysis — OTHER
    Obtain thoracolumbar morphometry in DXA scan, then determine presence and severity of vertebral compression fractures by VFA
  • Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire — OTHER
    Calculate patient-reported total pain scores to determine the pain phenotype of each study participant

Study Details

A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease

Key Dates

Start date
Nov 3, 2022
Status verified
Aug 2025
Primary completion
Apr 30, 2024
Completion
Jul 31, 2026

Study Design

Enrollment
53 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Other: SCD Bone Pain Study Cohort
    Prospective cohort of 50 adults with sickle cell disease (SCD) undergoing research DXA scan to assess bone mineral density and thoracolumbar morphometry for vertebral fracture analysis

Primary Outcome Measure

Lumbar Spine Bone Mineral Density [ Time Frame: Baseline ]

Locations (1)

FacilityCityStateZIPSite coordinators
UC Davis Comprehensive Cancer CenterSacramentoCalifornia95817-

Find similar trials in Sacramento, CA

By condition
Sickle cell disease
By research site
UC Davis Comprehensive Cancer Center· Sacramento, CA

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