Diffusion MRI of the Abdomen

Conditions

• Abdominal Imaging

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Diffusion Weighted Magnetic Resonance Imaging — DEVICE
  Diffusion-weighted (DW)-MRI has a unique ability to probe tissue microstructure without the need for ionizing radiation or intravenous contrast agents. DW-MRI of the abdomen is utilized in detection, staging, and treatment surveillance of malignancies, and has shown great promise in various other applications, including for the assessment of fibrosis in the liver, pancreas, kidneys, and other organs.

Study Details

The purpose of this research is to see if a new magnetic resonance imaging (MRI) method will be able to improve the images taken of the abdomen. This new method includes some changes to help avoid movements that may disrupt the images like breathing, heartbeats and other involuntary motion that occurs in the abdomen. This study will these methods in healthy volunteers and validate them in patients with known liver metastases in a single contrast-enhanced MRI visit.

Key Dates

Start date

Nov 22, 2023

Status verified

Nov 2025

Primary completion

Jun 30, 2026

Completion

Jun 30, 2026

Study Design

Enrollment

80 participants (estimated)

Arms

• Arm: Healthy Volunteers
• Arm: Known Liver Metastases

Primary Outcome Measure

Squared difference between each pair of repeated ADC measurements [ Time Frame: up to 1.5 hours ]

Central Contacts

• Radiology Studies
  608-282-8349
  [email protected]

Locations (1)

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