Genetic Susceptibility to Periprosthetic Joint Infections

Part of paid clinical trials in Salt Lake City, Utah.

Sponsor
University of Utah
Study ID
NCT05159739
Status
Enrolling By Invitation

Conditions

  • Periprosthetic Joint Infections
  • Total Joint Arthroplasty

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Blood Draw or Saliva/Cheek Cell Sample: — GENETIC
    Collected samples will immediately undergo genetic analysis to determine the presence or absence of potential candidate genes responsible for the increased incidence of PJI.

Study Details

The investigators primary objective is to identify genetic factors that may increase the risk of patients developing a periprosthetic joint infections (PJI) following total joint arthroplasty (TJA). The investigators hope that by identifying genetic predispositions we will be able to provide patient specific care pathways to prevent or minimize the risk for PJI.

Key Dates

Start date
Mar 7, 2018
Status verified
Mar 2026
Primary completion
Mar 31, 2028
Completion
Mar 31, 2028

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: Total Joint Arthroplasty (TJA)
    Recruitment of families with an increased incidence of TJI with PJI.

Primary Outcome Measure

Genotyping [ Time Frame: DNA extraction and analysis will be performed immediately after collection of blood draw or saliva/cheek cell sample by a certified core lab ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Utah Orthopaedic CenterSalt Lake CityUtah84108-

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By research site
University of Utah Orthopaedic Center· Salt Lake City, UT

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