Liquid Biopsies in Pediatric Solid Tumors
Part of paid clinical trials in Los Angeles, California.
- Sponsor
- Children's Hospital Los Angeles
- Study ID
- NCT05068583
- Status
- Recruiting
Conditions
- Pediatric Solid Tumor, Unspecified, Protocol Specific
Eligibility Criteria
- Sex
- ALL
- Age
- 6 Months - N/A
- Healthy Volunteers
- Accepted
Interventions
- Blood Draw — OTHERBlood draw at baseline, disease evaluation time point, and pre and post surgery and/or radiation.
Study Details
This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment. We will analyze the tumor material to see if it is similar to tumor tissue and if the tumor material in blood is helpful in monitoring the disease.
Key Dates
- Start date
- May 8, 2019
- Status verified
- Aug 2024
- Primary completion
- May 8, 2029
- Completion
- May 8, 2034
Study Design
- Enrollment
- 320 participants (estimated)
Arms
- Arm: Osteosarcoma
- Arm: Ewing Sarcoma
- Arm: Rhabdomyosarcoma
- Arm: Synovial Sarcoma
- Arm: Non-Rhabdomyosarcoma Soft Tissue Sarcoma
- Arm: Hepatic Tumors
- Arm: Renal Tumors
- Arm: Thyroid Tumors
- Arm: Germ Cell Tumors
- Arm: Healthy Volunteers
Primary Outcome Measure
To detect circulating tumor DNA (ctDNA) in serial blood samples from patients with pediatric non-CNS solid tumors using low pass whole genome sequencing. [ Time Frame: 10 years ]
Central Contacts
- Fariba Navid, MD323-361-2529
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | Anya Zdanowicz 323-361-5418 |
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