Laser Interstitial Thermal Ablation and Stereotactic Radiosurgery for Patients With Spine Metastases

Part of paid clinical trials in Detroit, Michigan.

Sponsor
Henry Ford Health System
Study ID
NCT05023772
Status
Recruiting
Apply to this trial

Conditions

  • Neoplasm Metastasis
  • Spinal Cord Compression
  • Spinal Cord Diseases
  • Spinal Cord Tumor
  • Spine Metastases

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Stereotactic Laser Ablation — PROCEDURE
    MR Guided laser ablation therapy
  • Stereotactic Radiosurgery — RADIATION
    Precise delivery of radiation to spinal tumor
  • MRI guided laser ablation — DIAGNOSTIC_TEST
    Surgery will take place in intraoperative suite to include operating room and MRI scanner

Study Details

The purpose of this research is to combine two complementary modes of treatment, spinal interstitial laser ablation and stereotactic spine radiosurgery (SSRS) for the treatment for spinal tumors near the spinal cord with an objective to improve tumor control, improve pain control, preserve function, and improve quality of life. We will also assess how effective these combined modes of treatment are in patients with spinal metastasis with an epidural component.

Key Dates

Start date
Sep 2, 2021
Status verified
Jun 2026
Primary completion
Sep 1, 2027
Completion
Jun 20, 2028

Study Design

Enrollment
60 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Experimental Treatment of Laser Interstitial Thermal Ablation Therapy and Stereotactic Radiosurgery
    Patients will undergo laser interstitial thermal ablation and CT guided stereotactic radiosurgery via intensity-modulated radiation therapy on different dates within a one to fourteen day window. The order of treatment is at the treating physicians discretion.

Primary Outcome Measure

Local Tumor Control Rate [ Time Frame: up to 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Henry Ford HospitalDetroitMichigan48202
RAMONA DAVIS
[email protected]
3132821753
REHNUMA NEWAZ
[email protected]
3139164123
IAN LEE, MD, FAANS (PRINCIPAL_INVESTIGATOR)
ADAM ROBIN, MD (SUB_INVESTIGATOR)
MIRA SHAH, MD (SUB_INVESTIGATOR)
SALIM SIDDIQUI, MD,PHD (SUB_INVESTIGATOR)

Find similar trials in Detroit, MI

By research site
Henry Ford Hospital· Detroit, MI

Related Studies