Autologous Mitochondrial Transplant for Cerebral Ischemia

Part of paid clinical trials in Seattle, Washington.

Sponsor
University of Washington
Study ID
NCT04998357
Status
Recruiting
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Conditions

  • Cerebral Ischemia

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Endovascular autologous mitochondrial transplantation — OTHER
    During standard-of-care endovascular reperfusion procedure, subjects will have autologous mitochondria infused via microcatheter into ischemic brain.

Study Details

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

Key Dates

Start date
Apr 29, 2021
Status verified
May 2025
Primary completion
Apr 29, 2026
Completion
Oct 29, 2026

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Transplantation
    Endovascular infusion

Primary Outcome Measure

Incidence of severe adverse events during mitochondrial infusion [ Time Frame: Through completion of reperfusion therapy, up to one hour post-infusion ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Harborview Medical CenterSeattleWashington98104
Melanie Walker, MD
206-744-3000
Michael Levitt, MD (SUB_INVESTIGATOR)

Find similar trials in Seattle, WA

By research site
Harborview Medical Center· Seattle, WA

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