Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

Conditions

• Arthritis Shoulder

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Glenohumeral Injection — PROCEDURE
  Patients who enroll will be randomized into an injection group, and then will undergo the specified injection at one time point only.

Study Details

The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This study will help elucidate the therapeutic benefit of corticosteroid and Platelet Rich Plasma (PRP) injections in this patient population.

Key Dates

Start date

Mar 13, 2023

Status verified

Feb 2026

Primary completion

Jan 31, 2027

Completion

Jan 31, 2028

Study Design

Enrollment

200 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Experimental: Corticosteroid Injection Group
  80mg Depo-Medrol and 8cc Lidocaine ultrasound-guided intra-articular injection
• Active Comparator: Platelet-Rich Plasma Injection Group
  15cc blood draw in Arthrex Autologous Conditioned Plasma (ACP) kit and processed per manufacturer instructions Ultrasound-guided intra-articular injection of isolated PRP

Primary Outcome Measure

Visual Analog Scale-Pain (VAS) [ Time Frame: 12 weeks ]

Central Contacts

• Carla M Edwards, PhD
  312.563.5735
  [email protected]

Locations (1)

Find similar trials in Chicago, IL