The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study

Part of paid clinical trials in New Orleans, Louisiana.

Sponsor
Tulane University
Study ID
NCT04947657
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Study Details

The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden. Secondary objectives of the study are the following: * To investigate the impact of catheter ablation on serum pro-thrombotic biomarkers in patients with AF. * To correlate coagulation biomarkers with imaging features such as, the degree of fibrosis found on Late Gadolinium Enhancement Magnetic Resonance Imaging (LGE-MRI) scans, which is a part of standard of care. * To determine baseline values of coagulation and pro-thrombotic biomarkers in the AF population and compare those baseline values with the general population values. * To compare central and peripheral thrombotic biomarkers in patients with atrial fibrillation.

Key Dates

Start date
Sep 22, 2021
Status verified
Mar 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
20 participants (estimated)

Primary Outcome Measure

Measure the change in Asymmetric dimethyl arginine (ADMA) in relation to atrial fibrillation burden [ Time Frame: Day 0, Day 1, Day 2, Day 30, Day 90 ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
East Jefferson General HospitalNew OrleansLouisiana70006
Mayana Bsoul, MD
[email protected]
504-988-3063
Kunal Sameer, MD, MHA
[email protected]
504-988-3072
Amitabh Pandey, MD (PRINCIPAL_INVESTIGATOR)
Tulane Doctors - Speciality Care - NapoleonNew OrleansLouisiana70115
Mayana Bsoul, MD
[email protected]
504-988-3063
Kunal Sameer, MD, MHA
[email protected]
504-988-3072
Amitabh Pandey, MD (PRINCIPAL_INVESTIGATOR)
University Medical CenterNew OrleansLouisiana70112
Mayana Bsoul, MD
[email protected]
504-988-3063
Kunal Sameer, MD, MHA
[email protected]
504-988-3072
Amitabh Pandey, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in New Orleans, LA

By condition
Atrial fibrillation
By specialty
CardiologyHeart disease
By research site
East Jefferson General Hospital· New Orleans, LATulane Doctors - Speciality Care - Napoleon· New Orleans, LAUniversity Medical Center· New Orleans, LA

Related Studies