Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.

Part of paid clinical trials in Loma Linda, California.

Sponsor
Loma Linda University
Study ID
NCT04860141
Phase
PHASE4
Status
Recruiting
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Conditions

  • Dental Pain and Sensation Disorder
  • Pain, Postoperative

Eligibility Criteria

Sex
ALL
Age
18 Years - 59 Years
Healthy Volunteers
Accepted

Interventions

  • Gabapentin 600mg — DRUG
    The patient will take gabapentin 600mg 2 hours prior to the procedure
  • Placebo — DRUG
    the patient will take a pill that looks like gabapentin 2 hours prior to the procedure

Study Details

This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, severity of pain, the number of analgesics taken, and side effect profiles (e.g. nausea/vomiting, dizziness) at the following intervals, 4 hour, 8 hour, 12 hour, 24, and 72 hour post-procedure.

Key Dates

Start date
Jun 16, 2021
Status verified
Feb 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
98 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Gabapentin group
    The patient in this group will take gabapentin 600mg PO 2 hours prior to his or her surgery.
  • Placebo Comparator: Placebo group
    The patient in this group will take a placebo that looks like gabapentin PO 2 hours prior to his or her surgery.

Primary Outcome Measure

opioid use [ Time Frame: 4 hour postoperatively ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Loma Linda University HealthLoma LindaCalifornia92354-

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Loma Linda University Health· Loma Linda, CA

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