A Study of Camrelizumab Combined Apatinib in Hepatocellular Carcinoma Previously Treated With Immune Checkpoint Inhibitors (ICIs).
- Sponsor
- Hunan Cancer Hospital
- Study ID
- NCT04826406
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Hepatocellular Carcinoma
- Immune Checkpoint Inhibitors
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Camrelizumab combined Apatinib regimen — DRUGCamrelizumab 200mg iv every 2 weeks; Apatinib,250 mg/day.
Study Details
The purpose of this study is to observe and preliminary explore the efficacy and safety of the combination of Camrelizumab and Apatinib regimen in treating advanced hepatocellular carcinoma (HCC) participants who have progressed following prior Immune Checkpoint Inhibitors (ICIs) treatment.
Key Dates
- Start date
- Feb 3, 2021
- Status verified
- Mar 2021
- Primary completion
- Mar 2, 2022
- Completion
- Aug 30, 2023
Study Design
- Enrollment
- 40 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Camrelizumab+Apatinib
Primary Outcome Measure
Objective Response Rate (ORR) [ Time Frame: Up to approximately 12 months ]
Central Contacts
- Shanzhi Gu, MD+86-731-88651900
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