Association of Periodontal Inflammation on Immune Response in Wound Healing
Part of paid clinical trials in Lincoln, Nebraska.
- Sponsor
- University of Nebraska
- Study ID
- NCT04805320
- Status
- Recruiting
Conditions
- Inflammation of Mouth
Eligibility Criteria
- Sex
- ALL
- Age
- 21 Years - 70 Years
- Healthy Volunteers
- Accepted
Interventions
- Dental Extraction — PROCEDUREExtraction
Study Details
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken. The posterior tooth will be atraumatically extracted and a small soft tissue biopsy of the extraction site will be taken. At the two week follow-up, sutures will be removed and another small biopsy of soft tissue will be taken. Subjects will be seen again at 3 months for a final collection of clinical data and radiographs.
Key Dates
- Start date
- Sep 1, 2021
- Status verified
- Dec 2025
- Primary completion
- Jun 30, 2026
- Completion
- Jul 31, 2026
Study Design
- Enrollment
- 25 participants (estimated)
Primary Outcome Measure
Inflammatory cells [ Time Frame: 3 months ]
Central Contacts
- Amy C Killeen, DDS402-472-7848
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Nebraska, College of Dentistry | Lincoln | Nebraska | 68583 | Amy C Killeen, DDS, MS (PRINCIPAL_INVESTIGATOR) |
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