The Possible Effects of Roflumilast on Obesity Related Disorders
- Sponsor
- Tanta University
- Study ID
- NCT04800172
- Phase
- PHASE3
- Status
- Completed
Conditions
- Obesity
- PreDiabetes
Eligibility Criteria
- Sex
- ALL
- Age
- 25 Years - 65 Years
- Healthy Volunteers
- Not accepted
Interventions
- Roflumilast — DRUGadministration of roflumilast 500 mcg tablet once daily for 3 months.
- placebo — DRUGadministration of placebo tablet once daily for 3 months.
Study Details
Evaluation of the possible effects of roflumilast on weight, glucose and lipid metabolism, insulin resistance, oxidative stress and inflammatory process in prediabetic obese subjects.
Key Dates
- Start date
- May 1, 2021
- Status verified
- Apr 2022
- Primary completion
- Mar 31, 2022
- Completion
- Mar 31, 2022
Study Design
- Enrollment
- 66 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Active Comparator: Roflumilast arm
- Placebo Comparator: Placebo arm
Primary Outcome Measure
Change in patients body weight [ Time Frame: baseline and 3 months later ]
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