A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol

Part of paid clinical trials in Albuquerque, New Mexico.

Sponsor
The Mind Research Network
Study ID
NCT04770025
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
21 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • High-density transcranial alternating current stimulation — DEVICE
    High-density electrode configuration with transcranial alternating current stimulation in the beta (15-40Hz) frequency range
  • Sham stimulation — DEVICE
    High-density electrode configuration with sham stimulation
  • Motivational interviewing — BEHAVIORAL
    Motivational interviewing session focused on alcohol use, approximately 30 minutes in length

Study Details

The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at above the low-risk level. Participants will be randomized to receive either MI with active stimulation, MI with sham stimulation, or a delayed treatment group that receives MI with no stimulation. Measures will include brain imaging, alcohol use, cannabis use, risk-taking behavior, emotions, and others. Participants who are randomized to the delayed-treatment group will not receive brain imaging.

Key Dates

Start date
Sep 1, 2020
Status verified
May 2025
Primary completion
Dec 31, 2025
Completion
Feb 28, 2026

Study Design

Enrollment
75 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: MI with tACS
    Motivational interviewing with concurrent active stimulation
  • Sham Comparator: MI with sham
    Motivational interviewing with concurrent sham stimulation
  • Active Comparator: MI-only
    Motivational interviewing only, delayed treatment control

Primary Outcome Measure

Heavy drinking days [ Time Frame: One month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The Mind Research NetworkAlbuquerqueNew Mexico87106
Jon M Houck, PhD
[email protected]
505-925-2372

Find similar trials in Albuquerque, NM

By condition
Substance use disorder
By specialty
Behavioral healthAddiction medicine
By research site
The Mind Research Network· Albuquerque, NM

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