Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT04753996
Status
Recruiting
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Conditions

  • Cholangiocarcinoma
  • PSC
  • Primary Sclerosing Cholangitis

Eligibility Criteria

Sex
ALL
Age
18 Years - 85 Years
Healthy Volunteers
Accepted

Study Details

The purpose of this research is to create a collection of bile, bile duct brushings and medical information from people with Primary Sclerosing Cholangitis (PSC) and controls to learn more about changes that occur in the liver.

Key Dates

Start date
Mar 8, 2021
Status verified
Feb 2026
Primary completion
Jan 1, 2035
Completion
Jan 1, 2035

Study Design

Enrollment
300 participants (estimated)

Arms

  • Arm: Primary Sclerosing Cholangitis (PSC)
    Subjects diagnosed with Primary Sclerosing Cholangitis (PSC) will be asked to provide bile and/or brush cytology at time of endoscopic retrograde cholangiopancreatography (ERCP) or cholecystectomy (gallbladder removal).
  • Arm: Control (non-PSC)
    Subjects without a diagnosis of Primary Sclerosing Cholangitis (PSC) will be asked to provide bile and/or brush cytology at time of endoscopic retrograde cholangiopancreatography (ERCP) or cholecystectomy (gallbladder removal).

Primary Outcome Measure

Number of participants in study. [ Time Frame: 20 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Erik M Schlicht, B.A.,CCRP
[email protected]
507-284-4312
Jackie Bianchi
[email protected]
507-266-0346

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