Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT04717869
Status
Recruiting
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Conditions

  • Frailty
  • Sarcopenia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ultrasound — DIAGNOSTIC_TEST
    2D ultrasound image collection
  • Biomarker Analysis — DIAGNOSTIC_TEST
    Inflammatory and nutritional biomarker analysis
  • Frailty Index — OTHER
    A Frailty Index Questionnaire be completed by patients or their surrogates to determine the presence of frailty at ICU admission

Study Details

Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential targets to reduce frailty.

Key Dates

Start date
Sep 22, 2023
Status verified
Jan 2026
Primary completion
May 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
250 participants (estimated)

Arms

  • Arm: ICU Patients
    Adult Surgical, Cardiothoracic, and Neuro- ICU patients will be enrolled within 48 hrs of admission

Primary Outcome Measure

Discharge Disposition [ Time Frame: Patients will be followed from enrollment to hospital discharge. Approximately 2 weeks to 2 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative MedicineLos AngelesCalifornia90095
Jennifer Scovotti, MA
[email protected]
3102064484
Cecilia Canales, MD, MPH (PRINCIPAL_INVESTIGATOR)
Maxime Cannesson, MD, Ph.D (SUB_INVESTIGATOR)
Vadim Gudzenko, MD (SUB_INVESTIGATOR)
Sumit Singh, MD (SUB_INVESTIGATOR)

Find similar trials in Los Angeles, CA

By research site
Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine· Los Angeles, CA

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