HIV Treatment Adherence Dose Determination Trial

Part of paid clinical trials in Storrs, Connecticut.

Sponsor
University of Connecticut
Study ID
NCT04577313
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Behavioral Self-Regulation Adherence Counseling — BEHAVIORAL
    Telephone-delivered counseling to focus on cognitive-behavioral skills to improve HIV treatment adherence.

Study Details

The proposed research will conduct the first dose-determination trial to find the optimal number of behavioral counseling sessions (dose) needed to achieve and sustain optimal HIV treatment adherence. The results of this study will determine how much intervention is needed for whom and at what cost to guide health policy and implementation of behavioral interventions designed to improve durable viral suppression.

Key Dates

Start date
Sep 1, 2020
Status verified
Aug 2025
Primary completion
Nov 30, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
400 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Continuous Counseling
    Receives up to 16 weekly behavioral counseling sessions over the phone to achieve optimal medication adherence. Counseling adjusts to patient needs and determines the dose to achieve optimal adherence / HIV suppression, in contrast to the fixed dose condition that does not adjust to patient response.
  • Active Comparator: Fixed Counseling
    Receives up to five weekly behavioral counseling sessions over the phone focused on improving HIV medication adherence / viral suppression.

Primary Outcome Measure

Change in Antiretroviral Therapy Adherence from Baseline to 12-Months [ Time Frame: 12-Month ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
University of ConnecticutStorrsConnecticut06269
Seth Kalichman, PhD
[email protected]
860-208-3706
Seth Kalichman, PhD (PRINCIPAL_INVESTIGATOR)
University of Connecticut Field SiteAtlantaGeorgia30308
Seth Kalichman, PhD
[email protected]
860-208-3706

Find similar trials in Storrs, CT

By condition
HIV
By specialty
Infectious disease
By research site
University of Connecticut· Storrs, CTUniversity of Connecticut Field Site· Atlanta, GA

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