Radiotherapy Combined With Irinotecan and Apatinib Followed by PD-1 Antibody and Apatinib for Advanced Solid Tumors
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- Study ID
- NCT04569916
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Solid Tumor
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 70 Years
- Healthy Volunteers
- Not accepted
Interventions
- radiotherapy — RADIATIONradiotherapy combined with irinotecan liposome and apatinib followed by PD-1 antibody and apatinib
- irinotecan liposome — DRUGradiotherapy combined with irinotecan liposome and apatinib followed by PD-1 antibody and apatinib
- apatinib — DRUGradiotherapy combined with irinotecan liposome and apatinib followed by PD-1 antibody and apatinib
- PD-1 antibody — DRUGradiotherapy combined with irinotecan liposome and apatinib followed by PD-1 antibody and apatinib
Study Details
An exploratory study to evaluate for the treatment of advanced solid tumors that failed standard treatments.
Key Dates
- Start date
- Sep 30, 2020
- Status verified
- Sep 2020
- Primary completion
- Feb 28, 2023
- Completion
- May 31, 2023
Study Design
- Enrollment
- 30 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: treatment groupradiotherapy combined with irinotecan liposome and apatinib followed by PD-1 antibody and apatinib
Primary Outcome Measure
Objective Response Rate [ Time Frame: 2 years ]
Central Contacts
- Jie Shen, Doctor13675101127
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