Auricular VNS Following Subarachnoid Hemorrhage

Part of paid clinical trials in St Louis, Missouri.

Sponsor
Anna Huguenard
Study ID
NCT04557618
Status
Recruiting
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Conditions

  • Subarachnoid Hemorrhage

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Auricular Vagus Nerve Stimulation — DEVICE
    Transcutaneous auricular vagal nerve stimulation
  • Sham Auricular Vagus nerve Stimulation — DEVICE
    Transcutaneous auricular vagal nerve ear clip applied without current

Study Details

This study will evaluate whether non-invasive auricular vagal nerve stimulation lowers inflammatory markers, and improves outcomes following spontaneous subarachnoid hemorrhage.

Key Dates

Start date
Jan 5, 2021
Status verified
Dec 2025
Primary completion
Jun 30, 2026
Completion
Dec 31, 2028

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Auricular VNS Stimulation
    Participants receive twice daily auricular vagal nerve stimulation
  • Sham Comparator: Sham Auricular VNS Stimulation
    Participants will have an auricular vagal nerve stimulator applied twice daily, without the stimulation applied

Primary Outcome Measure

Inflammatory markers in the serum on admission [ Time Frame: On hospital day 1 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Washington University School of MedicineSt LouisMissouri63110
Anna Huguenard, MD
[email protected]
3144506698

Find similar trials in St Louis, MO

By research site
Washington University School of Medicine· St Louis, MO

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