Open Label Study of the Effects of Secukinumab on Nail Psoriasis and Non-Invasive Measures of Enthesitis (Phase IV)
Part of paid clinical trials in Philadelphia, Pennsylvania.
- Sponsor
- University of Pennsylvania
- Study ID
- NCT04535999
- Phase
- PHASE4
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 85 Years
- Healthy Volunteers
- Not accepted
Interventions
- Secukinumab Auto-Injector — DRUG300 mg- Every 4 weeks after loading dose (Loading Dose-300 mg once weekly for 5 weeks)
Study Details
This study will be an open label study of secukinumab for the treatment of nail psoriasis. Secukinumab is an FDA-approved treatment for psoriasis. We will examine time to response and different methods of defining nail disease response.
Key Dates
- Start date
- Feb 7, 2022
- Status verified
- Jul 2025
- Primary completion
- May 30, 2025
- Completion
- May 30, 2025
Study Design
- Enrollment
- 16 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Open LabelSecukinumab
Primary Outcome Measure
NAPSI [ Time Frame: Baseline to 24 Weeks ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Hospital at the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | - |
Find similar trials in Philadelphia, PA
By condition
By specialty
By research site
Related Studies
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVOPHASE1 · Recruiting · National Cancer Institute (NCI) · Birmingham, Alabama
- Study of SFA002 in Patients with Mild to Moderate Psoriasis PlaquesPHASE1 · Recruiting · SFA Therapeutics · Pompano Beach, Florida
- A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)PHASE4 · Recruiting · Eli Lilly and Company · Phoenix, Arizona
- Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy ProjectRecruiting · University of California, San Diego · La Jolla, California