Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Illinois at Chicago
Study ID
NCT04477330
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Transcranial direct current stimulation (tDCS) — OTHER
    1 mA tDCS
  • Ankle motor training — OTHER
    Visuomotor target tracking task
  • High intensity interval speed based treadmill training (HIISTT) — BEHAVIORAL
    Each treadmill session to include warm-up, high intensity speed-based intervals interleaved with active recovery, and cool down.

Study Details

Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged as a promising adjuvant to conventional rehabilitation. This project focuses on the development of a long term gait rehabilitation protocol using brain stimulation to improve walking outcomes in people with stroke. The project will also aim to understand the neural mechanisms that are associated with response to the intervention.

Key Dates

Start date
Sep 1, 2020
Status verified
Aug 2025
Primary completion
Dec 31, 2026
Completion
Aug 31, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Priming+HIISTT
    Facilitatory transcranial direct current stimulation (tDCS) and ankle motor training before high intensity interval speed based treadmill training
  • Sham Comparator: Sham+HIISTT
    Sham tDCS before high intensity interval speed based treadmill training

Primary Outcome Measure

Walking speed with 10 meter walk test [ Time Frame: Change from baseline to immediately after training and baseline to 3 months follow up ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Physical TherapyChicagoIllinois60612
Sangeetha Madhavan
[email protected]

Find similar trials in Chicago, IL

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Physical Therapy· Chicago, IL

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