Generating Novel Therapeutic Strategies Based on Evolutionary Tumor Board

Part of paid clinical trials in Tampa, Florida.

Sponsor
H. Lee Moffitt Cancer Center and Research Institute
Study ID
NCT04343365
Status
Recruiting

Conditions

  • Incurable Disease

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Evolutionary Tumor Board (ETB) — OTHER
    The ETB consists of evolutionary biologists, mathematicians, research scientists, statisticians,data scientists, radiologists, pathologists, oncologists (surgical, radiation, medical, and pediatric), and clinical trial coordinators.The ETB will generate hypotheses, mathematical models, and experiments from the discussion towards further integration of evolutionary ideas towards therapeutic strategies for participants. The ETB will collect data through a chart review regarding adherence and results of ETB recommendation

Study Details

This study will evaluate the ability of a multidisciplinary group, the Evolutionary Tumor Board (ETB), to develop therapeutic strategies in patients without curative options.

Key Dates

Start date
May 5, 2020
Status verified
Mar 2026
Primary completion
Mar 31, 2028
Completion
Mar 31, 2028

Study Design

Enrollment
35 participants (estimated)

Arms

  • Arm: Participants Reviewed by ETB
    Participants clinical history, available therapeutic options, and outcome expectations will be presented to the Evolutionary Tumor Board (ETB) along with images and pathology. Strategies and models will be presented regarding additional evolutionary ideas that can be applied.

Primary Outcome Measure

ETB developing therapeutic strategies [ Time Frame: Baseline to up to 60 months from end of therapy ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Moffitt Cancer CenterTampaFlorida33613
Sara Donadelli
813-745-8111
Jingsong Zhang, MD (PRINCIPAL_INVESTIGATOR)
Joel Brown, PhD (SUB_INVESTIGATOR)
Alexander Anderson, PhD (SUB_INVESTIGATOR)
Michael Schell, PhD (SUB_INVESTIGATOR)
Christine Chung, MD (SUB_INVESTIGATOR)

Find similar trials in Tampa, FL