Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Northwestern University
Study ID
NCT04312269
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
21 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Targeted Memory Reactivation (TMR) — OTHER
    Targeted memory reactivation (TMR) refers to the process of playing audio cues associated with specific learned material quietly during sleep in order to strengthen consolidation of specific memories during sleep.

Study Details

This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.

Key Dates

Start date
Feb 25, 2020
Status verified
May 2026
Primary completion
Jan 30, 2027
Completion
Jan 30, 2027

Study Design

Enrollment
70 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: All phase TMR
    TMR during every stage of sleep
  • Experimental: Slow-wave sleep (SWS) only TMR
    TMR during slow-wave sleep only
  • Experimental: Reduced frequency TMR
    TMR during only subset of sessions
  • Sham Comparator: Sham TMR
    Patients receive no TMR

Primary Outcome Measure

Wolf Motor Function Test (WMFT) [ Time Frame: change from baseline at 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Northwestern UniversityChicagoIllinois60611-

Find similar trials in Chicago, IL

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Northwestern University· Chicago, IL

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