Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)

Part of paid clinical trials in Los Angeles, California.

Sponsor
Andover Eye Associates
Study ID
NCT04296864
Phase
PHASE2
Status
Unknown

Conditions

  • Atopic Keratoconjunctivitis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

This is a multi-center, double-masked, randomized, placebo-controlled, parallel-group, efficacy, safety, and tolerability study evaluating the efficacy of Dupilumab in the treatment of signs and symptoms of atopic keratoconjunctivitis (AKC).

Key Dates

Start date
Feb 10, 2020
Status verified
Jan 2024
Primary completion
Jan 31, 2025
Completion
Jan 31, 2025

Study Design

Enrollment
42 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Placebo Comparator: Placebo
    Placebo of Dupilumab
  • Experimental: Dupilumab
    one loading dose of Dupilumab 600 mg followed by Dupilumab 300 mg weekly for a total of 16 weeks

Primary Outcome Measure

Percentage of treatment responders [ Time Frame: Baseline to Week 16 ]

Central Contacts

Locations (20)

FacilityCityStateZIPSite coordinators
Premiere Practice Management, LLCLos AngelesCalifornia90013-
Colorado Eye Consultants/Corneal Consultants of ColoradoLittletonColorado80120-
Encore Medical Research, LLCHollywoodFlorida33021-
Kannar Eye CarePittsburgKansas66762
Megan Compton
Andover Eye AssociatesAndoverMassachusetts01810-
University of Michigan- Kellogg Eye CenterAnn ArborMichigan48105-
Silverstein Eye CentersKansas CityMissouri64133-
Mercy Clinic Eye SpecialistsSpringfieldMissouri65804-
Ophthalmology AssociatesSt LouisMissouri63131
Dawn Weimers
St. Louis Eye InstituteTown and CountryMissouri63017
Abigail Carpenter
Northwell Health Physician Partners Ophthalmology at Great NeckGreat NeckNew York11021-
Gerald W. Zaidman, MDHawthorneNew York10532-
NC Eye AssociatesApexNorth Carolina27502
Cheryl Salter
Vita Eye ClinicShelbyNorth Carolina28150-
Tracie MalsomFargoNorth Dakota58103
Kayla Geyer
Vantage EyeCare, LLC.Bala-CynwydPennsylvania19004-
Blink Research CenterMemphisTennessee38119
Brandy Robertson
Advancing Vision Research, LLCSmyrnaTennessee37167-
Eye Associates of Central TexasRound RockTexas78681-
Periman Eye InstituteSeattleWashington98119
Christeen DeNeui

Find similar trials in Los Angeles, CA

By research site
Premiere Practice Management, LLC· Los Angeles, CAColorado Eye Consultants/Corneal Consultants of Colorado· Littleton, COEncore Medical Research, LLC· Hollywood, FLKannar Eye Care· Pittsburg, KSAndover Eye Associates· Andover, MAUniversity of Michigan- Kellogg Eye Center· Ann Arbor, MI

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