Apatinib for Inoperable Advanced Chondrosarcoma
- Sponsor
- Peking University People's Hospital
- Study ID
- NCT04260113
- Status
- Completed
Conditions
- Efficacy
- Toxicity, Drug
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Apatinib Mesylate — DRUGApatinib orally 500mg once daily half an hour after meal
Study Details
Anti-angiogenesis Tyrosine kinase inhibitors (TKIs) have been proved to show promising effects on prolonging progression-free survival (PFS) for advanced chondrosarcoma after failure of standard multimodal Therapy. Methylsulfonic apatinib is one of those TKIs which specifically inhibits VEGFR-2. This study summarizes the experience of two Peking University affiliated hospitals in off-label use of apatinib in the treatment of extensively pre-treated chondrosarcoma.
Key Dates
- Start date
- Oct 1, 2019
- Status verified
- Jan 2021
- Primary completion
- Jan 1, 2020
- Completion
- Apr 1, 2020
Study Design
- Enrollment
- 40 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Apatinib Arm
Primary Outcome Measure
progression-free survival [ Time Frame: 6 months ]
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