PD-1 Monoclonal Antibody Plus Apatinib Combined With SBRT in HCC With PVTT
- Sponsor
- Huazhong University of Science and Technology
- Study ID
- NCT04165174
- Phase
- PHASE2
- Status
- Unknown
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Terepril monoclonal antibody; Apatinib — DRUGTerepril monoclonal antibody,240mg,ivdrip,Q3W Apatinib,250mg,po,QD
- SBRT — RADIATION6-10Gy/F,5-8F
Study Details
It is a trial to assess the efficacy and safety of PD-1 monoclonal antibody plus Apatinib combined with SBRT as first-line treatment in HCC with PVTT.
Key Dates
- Start date
- Dec 31, 2019
- Status verified
- Nov 2019
- Primary completion
- Nov 30, 2020
- Completion
- Dec 31, 2020
Study Design
- Enrollment
- 20 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: PASPD-1:240mg,ivdrip,Q3W,begin with SBRT Apatinib:250mg,po,QD,begin with SBRT SBRT:6-10Gy/F,5-8F
Primary Outcome Measure
PFS [ Time Frame: up to 3 years ]
Central Contacts
- Xianglin Yuan, MD,PhD8627-83663406
- Yanmei Zou, MD,PhD8627-83663406
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