Adolescent Attention to Emotion Study

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT04105868
Status
Completed

Conditions

Eligibility Criteria

Sex
FEMALE
Age
13 Years - 15 Years
Healthy Volunteers
Accepted

Interventions

  • Neurofeedback — OTHER
    Participants will receive feedback during a computerized task that is based on their own visuocortical activity evoked by attention to negative distractors and task-relevant stimuli on the computer screen.

Study Details

Rates of depression increase rapidly during adolescence, especially for girls, and, thus, research is needed to spur the development of novel interventions to prevent adolescent depression. This project seeks to determine if a novel visuocortical probe of affect-biased attention (i.e., steady-state visual evoked potentials derived from EEG) can 1) be used to prospectively predict depression using a multi-wave repeated measures design and 2) modify affect-biased attention and buffer subsequent mood reactivity using real time neurofeedback. This work could ultimately lead to improved identification of adolescents who are at high risk for depression and directly inform the development of mechanistic treatment targets to be used in personalized intervention prescriptions for high-risk youth.

Key Dates

Start date
Oct 16, 2019
Status verified
Oct 2025
Primary completion
Sep 23, 2024
Completion
Mar 30, 2025

Study Design

Enrollment
15 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Neurofeedback
    Participants will receive feedback about their attention to negative distractors during each trial using activity from their brain waves, which will help them reduce their attention to distractors.

Primary Outcome Measure

Affect-biased Attention Following Neurofeedback (Immediately Post-Intervention) [ Time Frame: Approximately 1 hour total: baseline assessment immediately before neurofeedback and post-neurofeedback assessment immediately after the ~1 hour training session on the same day. ]

Locations (1)

FacilityCityStateZIPSite coordinators
Western Psychiatric Institute and ClinicPittsburghPennsylvania15213-

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