Vicryl Rapide Versus Nonabsorbable Suture

Conditions

• Traumatic Lacerations

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Vicryl Rapide absorbable suture — DEVICE
  In general, most laceration repair has been done with sutures on the surface of the skin that do not break down and fall off on their own, so after enough days have passed for the laceration to heal properly, the patient needs to return to the ED to have the sutures removed by cutting them off. These sutures are called "nonabsorbable". Some newer sutures have been designed to slowly dissolve on their own and fall out over several days. These are called "absorbable" sutures. You do not normally need to return to the ED for removal as these should slowly dissolve and fall out on their own.

Study Details

This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.

Key Dates

Start date

Sep 26, 2019

Status verified

Feb 2025

Primary completion

Sep 1, 2028

Completion

Jan 31, 2029

Study Design

Enrollment

96 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: Absorbable
  Wound repaired with Vicryl Rapide absorbable suture
• No Intervention: Nonabsorbable
  Wound repaired with traditional nonabsorbable suture

Primary Outcome Measure

The two treatments will be compared by a noninferiority test [ Time Frame: 3-Month ]

Central Contacts

• Brian Chinnock, MD
  559-499-6440
  [email protected]
• Jannet Castaneda, BA
  559-994-5893
  [email protected]

Locations (2)

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