Effects of Benaglutide on Weight and Gut Microbiota in Obese Patients

Sponsor
Xiangya Hospital of Central South University
Study ID
NCT03986008
Phase
PHASE3
Status
Unknown

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Benaglutide — DRUG
    The treatment of Benaglutide lasted three months.During the first week: 0.1mg per day;During the second week: 0.14mg per day; From third week onwards, 0.2mg per day.
  • Liraglutide — DRUG
    The treatment of Liraglutide lasted three months.During the first week: 0.6mg per day;During the second week: 1.2mg per day; From third week onwards, 1.8mg per day.

Study Details

The purpose of this studay is to evaluate the effects of Benaglutide on the treatment of subjects with obesity.

Key Dates

Start date
Dec 1, 2019
Status verified
Apr 2021
Primary completion
Dec 23, 2021
Completion
Dec 23, 2021

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Benaglutide
    Benaglutide will be administered three times a day by subcutaneous injection (under the skin) in the abdomen, thigh, or upper arm. It will be given 10 minutes before each meal.
  • Active Comparator: Liraglutide
    Liraglutide will be administered once a day by subcutaneous injection (under the skin) in the abdomen, thigh, or upper arm. It will be given independently of meals and preferably at the same each day.

Primary Outcome Measure

Weight Change at 3 months [ Time Frame: baseline and 3 months ]

Central Contacts

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