A Pancreatic Cancer Screening Study in Individuals With New-Onset or Deteriorating Diabetes Mellitus

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Nuvance Health
Study ID
NCT03937453
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • MRI/MRCP — DIAGNOSTIC_TEST
    An MRI/MRCP with IV gadolinium contrast with high resolution imaging of the pancreas will be performed at baseline. Further imaging upon recommendation by study committee

Study Details

The main goal of this study is to explore the relationship between new-onset diabetes mellitus/deteriorating diabetes and a subsequent diagnosis of pancreatic cancer. Magnetic Resonance Imaging and Magnetic cholangiopancreatography (MRI/MRCP) will be utilized to screen for early stage pancreatic cancer or precursor lesions. Participants will be asked to donate a blood sample at specific intervals for the creation of a bio-bank necessary for the development of a blood based screening test for pancreatic cancer.

Key Dates

Start date
Jan 19, 2018
Status verified
Apr 2026
Primary completion
Jan 19, 2028
Completion
Jan 19, 2028

Study Design

Enrollment
800 participants (estimated)

Arms

  • Arm: New-Onset Diabetes Mellitus
    Diabetes Mellitus diagnosed within the past 12 months
  • Arm: Deteriorating Diabetes Mellitus
    History of Diabetes Mellitus with recent deteriorating within the past 6 months confirmed with repeat testing and not associated with weight gain or diabetes medication non-compliance

Primary Outcome Measure

Early Stage Pancreatic Cancer or Precursor Lesions [ Time Frame: Through study completion, up to 3 years ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Yale UniversityNew HavenConnecticut06520
James J Farrell, MD (PRINCIPAL_INVESTIGATOR)
Nuvance HealthNorwalkConnecticut06856
Tammy Lo, MSN
[email protected]
203-855-3551
Richard Frank, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in New Haven, CT

By condition
Pancreatic cancer
By specialty
OncologyGI oncology
By research site
Yale University· New Haven, CTNuvance Health· Norwalk, CT

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