A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes

Part of paid clinical trials in Little Rock, Arkansas.

Sponsor
Eli Lilly and Company
Study ID
NCT03882970
Phase
PHASE3
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Insulin Degludec — DRUG
    Administered SC

Study Details

The purpose of this study is to compare the effect of the study drug tirzepatide to insulin degludec on blood sugar levels in participants with type 2 diabetes. The study will last about 67 weeks and may include up to 22 visits.

Key Dates

Start date
Apr 1, 2019
Status verified
Jan 2022
Primary completion
Dec 11, 2020
Completion
Jan 4, 2021

Study Design

Enrollment
1,444 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: 5 mg Tirzepatide
    5 milligrams (mg) tirzepatide administered subcutaneously (SC) once a week.
  • Experimental: 10 mg Tirzepatide
    10 mg tirzepatide administered SC once a week.
  • Experimental: 15 mg Tirzepatide
    15 mg tirzepatide administered SC once a week.
  • Active Comparator: Insulin Degludec
    Insulin degludec administered SC once a day.

Primary Outcome Measure

Change From Baseline in Hemoglobin A1c (HbA1c) (10 mg and 15 mg) [ Time Frame: Baseline, Week 52 ]

Locations (33)

FacilityCityStateZIPSite coordinators
Arkansas Clinical ResearchLittle RockArkansas72205-
Valley ResearchFresnoCalifornia93720-
National Research InstituteHuntington ParkCalifornia90255-
National Research InstituteLos AngelesCalifornia90057-
Catalina Research Institute, LLCMontclairCalifornia91763-
Valley Clinical Trials, Inc.NorthridgeCalifornia91325-
National Research InstitutePanorama CityCalifornia91402-
Encompass Clinical ResearchSpring ValleyCalifornia91978-
University Clinical Investigators, Inc.TustinCalifornia92780-
Chase Medical Research, LLCWaterburyConnecticut06708-
Indago Research & Health Center, Inc.HialeahFlorida33012-
East Coast Clinical ResearchJacksonvilleFlorida32204-
East Coast Institute For ResearchJacksonvilleFlorida32216-
Bayside Clinical Research, LLCNew Port RicheyFlorida34655-
East Coast Institute For ResearchMaconGeorgia31210-
Sky Clinical Research NetworkUnion CityGeorgia30291-
Elite Clinical Trials LLLPBlackfootIdaho83221-
Humphreys Diabetes CenterBoiseIdaho83702-
Rocky Mountain Diabetes and Osteoporosis CenterIdaho FallsIdaho83404-
Springfield Diabetes & Endocrine CenterSpringfieldIllinois62711-
Crescent City Clinical ResearchMetairieLouisiana70006-
Endocrine and Metabolic ConsultantsRockvilleMaryland20852-
Troy Internal Medicine, PCTroyMichigan48098-
International Diabetes CenterMinneapolisMinnesota55416-
Clinical Research ProfessionalsChesterfieldMissouri63005-
Palm Research CenterLas VegasNevada89128-
Palm Research CenterLas VegasNevada89148-
Aventiv ResearchColumbusOhio43213-
The Corvallis Clinic P.C.CorvallisOregon97330-
Heritage Valley Medical Group, Inc.BeaverPennsylvania15009-
Detweiler Family MedicineLansdalePennsylvania19446-
Office of Dr. Osvaldo BruscoCorpus ChristiTexas78414-
Consano Clinical ResearchShavano ParkTexas78231-

Find similar trials in Little Rock, AR

By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Arkansas Clinical Research· Little Rock, ARValley Research· Fresno, CANational Research Institute· Huntington Park, CANational Research Institute· Los Angeles, CACatalina Research Institute, LLC· Montclair, CAValley Clinical Trials, Inc.· Northridge, CA

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