Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV

Part of paid clinical trials in Providence, Rhode Island.

Sponsor
Brown University
Study ID
NCT03862924
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Standardized Research Electronic Cigarette — DEVICE
    Participants will receive SREC weekly and eill be encouraged to replace their usual combustible cigarette with the SREC whenever they would normally smoke.

Study Details

Cigarette smoking is more prevalent (50-70%) in persons living with HIV in the U.S. when compared with the general population and is linked to increased rates of heart disease, lung diseases and infections, and lung cancers. Because of their high levels of nicotine dependence, low quit rates, and familiarity with harm reduction, HIV-positive smokers may view the use of alternative nicotine delivery products, such as electronic cigarettes (ECs), as an attractive option for reducing and eventually stopping combustible cigarette use. However, little is known about the health effects of electronic cigarette use in HIV-positive smokers. Some studies have shown that electronic cigarette use was associated with increased confidence to quit smoking in the general population. The primary objectives of this project are to examine whether HIV-positive smokers, who are unwilling or unable to quit smoking, will substitute an electronic cigarette for regular cigarettes, and to examine whether there are any changes in heart and lung health in HIV-positive smokers who switch from regular cigarettes to electronic cigarettes.

Key Dates

Start date
Mar 1, 2022
Status verified
Jun 2024
Primary completion
Apr 30, 2024
Completion
Dec 30, 2024

Study Design

Enrollment
72 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Active condition
    Participants in the active condition will be provided with the Standardized Research Electronic Cigarette (SREC) and will be encouraged to use the SREC whenever they would normally smoke a cigarette.
  • No Intervention: Standard Condition
    Participants in this condition will be asked to continue to smoke their usual brand of cigarettes.

Primary Outcome Measure

Change in combustible cigarette use from baseline to 6 weeks [ Time Frame: 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Brown University School of Public HealthProvidenceRhode Island02912
Garrett Stang, MA
[email protected]
401-863-6011

Find similar trials in Providence, RI

By condition
HIV
By specialty
Infectious disease
By research site
Brown University School of Public Health· Providence, RI

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