Genetic and Epigenetic Basis of Chronic Wounds

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT03793062
Status
Recruiting
Apply to this trial

Conditions

  • Chronic Wounds

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • No Interventions — OTHER
    Not applicable - No Interventions

Study Details

This pilot study is designed for chronic wounds that fail to heal in a timely manner carry specific genetic signatures. These genetic signatures will be studied using debrided wound tissue that is removed by the wound care provider as part of standard of care. The reference genomic signature will be evaluated by obtaining blood samples and will be compared with wound debrided tissue genomic signature to understand wound specific genomic changes.

Key Dates

Start date
Dec 4, 2018
Status verified
Apr 2026
Primary completion
Jun 1, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
256 participants (estimated)

Primary Outcome Measure

Epigenetic and transcriptome changes in debrided tissue from chronic wounds in healing vs non healing phase . [ Time Frame: 16 weeks or healing whichever comes first ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UPMC Wound Care CentersPittsburghPennsylvania15213
Piya Das Ghatak, PhD, MS
[email protected]
6149064621
Urmila Gnyawali, CCRP
[email protected]
614-371-2028

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UPMC Wound Care Centers· Pittsburgh, PA

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