Compare Apatinib Plus Capecitabine Versus Capecitabine in Maintenance Therapy for Patients With Advanced Triple-negative Breast Cancer
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- Study ID
- NCT03775928
- Phase
- PHASE2
- Status
- Unknown
Conditions
- Triple-negative Breast Cancer
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Apatinib — DRUGapatinib 425mg qd po
- capecitabine — DRUGcapecitabine 1000mg/m2 bid d1-d14
Study Details
The purpose of this study is to assess the efficacy and safety of patients who receive apatinib plus capecitabine or capecitabine for maintenance therapy of patients with with advanced triple-negative breast cancer
Key Dates
- Start date
- Dec 18, 2018
- Status verified
- Dec 2018
- Primary completion
- Dec 1, 2020
- Completion
- Oct 1, 2021
Study Design
- Enrollment
- 80 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: Apatinib + CapecitabineApatinib 425mg d1-21+ capecitabine 1000mg/m2 bid d1-14, q21d
- Active Comparator: Capecitabinecapecitabine 1000mg/m2 bid d1-14, q21d
Primary Outcome Measure
progression-free survival [ Time Frame: up to 6 months ]
Central Contacts
- Binghe Xu86-87788826
- Bo Lan86-87788114
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