Utility of PCD Diagnostics to Improve Clinical Care

Conditions

• Primary Ciliary Dyskinesia

Eligibility Criteria

Sex

ALL

Age

1 Year - N/A

Healthy Volunteers

Not accepted

Interventions

• nNO testing — OTHER
  Collection of already performed clinical data and nNO testing

Study Details

This is a study evaluating the utility of current Primary Ciliary Dyskinesia (PCD) diagnostic tests, including nasal nitric oxide testing.

Key Dates

Start date

Jun 1, 2017

Status verified

Jun 2025

Primary completion

Jun 1, 2028

Completion

Jun 1, 2028

Study Design

Enrollment

200 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Arms

• Other: Nasal Nitric Oxide testing and collection of clinical data
  Participants will have nNO testing is indicated. All participants in this study have some basic clinical data collected at time of enrollment. Participants with a confirmed diagnosis of PCD or in those participants with a working diagnosis of PCD in which ongoing nNO testing is performed have prospective data collection. Some participants have a confirmed diagnosis of PCD by genetics or ciliary biopsy at time of study entry and thus do not need nNO testing, but are followed prospectively with collection of basic clinical data

Primary Outcome Measure

frequency of nNO tests performed [ Time Frame: 3 years ]

Central Contacts

• Michael O'Connor, MD
  615.343.7617
  [email protected]

Locations (1)

Find similar trials in Nashville, TN

Related Studies

• Use of Nasal Nitric Oxide Testing in Improving Primary Ciliary Dyskinesia Clinical Care
  Recruiting · Arkansas Children's Hospital Research Institute · Little Rock, Arkansas
• Utility of PCD Diagnostics to Improve Clinical Care
  Recruiting · Connecticut Children's Medical Center · Hartford, Connecticut
• Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia
  Recruiting · Indiana University · Indianapolis, Indiana