Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer
Part of paid clinical trials in La Jolla, California.
- Sponsor
- Hitendra Patel
- Study ID
- NCT03697564
- Phase
- PHASE2
- Status
- Completed
Conditions
- Pancreatic Cancer Stage IV
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Gemcitabine — DRUG1000 mg/m2 IV on days 1, 8, and 15 Q4W
- Nivolumab 10 MG/ML Intravenous Solution [OPDIVO] — DRUG480mg IV on Day 1 Q4W
- Cabiralizumab — DRUG4mg/kg IV on day 1 and 15 Q4W
Study Details
The purpose of this study is to see if the combination of nivolumab + cabiralizumab + gemcitabine can give prolonged disease control in patients with advanced pancreatic cancer compared to gemcitabine alone.
Key Dates
- Start date
- Oct 31, 2019
- Status verified
- Jul 2025
- Primary completion
- Apr 12, 2023
- Completion
- Jul 13, 2023
Study Design
- Enrollment
- 2 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: gemcitabine +nivolumab + cabiralizumabgemcitabine +nivolumab + cabiralizumab
Primary Outcome Measure
Number of Participants With Progression Free Survival (PFS) [ Time Frame: 6 months ]
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| UCSD Moores Cancer Center | La Jolla | California | 92093 | - |
Related coverage on Hipa.ai
- Nivolumab Combination Trial in Stage IV Pancreatic Cancer Posts Initial ResultsNivolumab · Aug 6, 2025 · ClinicalTrials.gov
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