Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Part of paid clinical trials in Miami, Florida.

Sponsor
Alzheimer's Light LLC
Study ID
NCT03657745
Status
Recruiting
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Conditions

  • Alzheimer Disease
  • Cognition Disorders in Old Age
  • Cognitive Decline
  • Cognitive Deterioration
  • Dementia
  • Mild Cognitive Impairment

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Combination of 40Hz light and cognitive therapy (ALZLIFE) — DEVICE
    Combination of 40Hz light and cognitive therapy delivered by iPad application ALZLIFE

Study Details

Electrical activity in the brain known as "gamma" brainwaves help connect and process information throughout the brain. These gamma waves are diminished in Alzheimer's disease. New research in Alzheimer's disease mouse models shows that exposure to light flickering at the rate of 40 flashes per second or 40Hz increased gamma brainwaves and led to clearing of beta amyloid plaques in the brain, a key abnormality in Alzheimer's disease. This project will test the ability of a novel iPad App (AlzLife https://www.alz.life/) that delivers light therapy at 40 Hz combined with cognitive therapy to improve cognition, function, and quality of life in Alzheimer's disease.

Key Dates

Start date
Jan 1, 2018
Status verified
Jul 2024
Primary completion
Dec 31, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Participants who adhere to the protocol
    All participants are encouraged to exercise with AlzLife daily for 30 minutes a day. The actual duration is to be measured through participant's interactions with ALZLIFE. Participants adhere to the protocol if they exercise with AlzLife the minimum of 1hour/week.
  • Arm: Participants who do not adhere to the protocol
    All participants are encouraged to exercise with AlzLife daily for 30 minutes a day. The actual duration is to be measured through participant's interactions with ALZLIFE. Participants do not adhere to the protocol if they exercise with AlzLife less than 1hour/week.

Primary Outcome Measure

In-app cognitive test [ Time Frame: through study completion, an average of 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Andrey VyshedskiyMiamiFlorida33156
Andrey Vyshedskiy
[email protected]
617-433-8577

Find similar trials in Miami, FL

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Andrey Vyshedskiy· Miami, FL

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