A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

Part of paid clinical trials in Palo Alto, California.

Sponsor
Incyte Corporation
Study ID
NCT03599713
Phase
PHASE2
Status
Completed

Conditions

  • Metastatic Merkel Cell Carcinoma

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Retifanlimab — DRUG
    INCMGA00012 administered at 500 milligrams (mg) by intravenous infusion once every 4 weeks

Study Details

The purpose of this study is to assess the clinical activity and safety of INCMGA00012 in participants with advanced/metastatic Merkel cell carcinoma (MCC).

Key Dates

Start date
Feb 25, 2019
Status verified
Aug 2025
Primary completion
Jan 21, 2022
Completion
Jun 28, 2024

Study Design

Enrollment
107 participants (actual)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Retifanlimab: Chemotherapy: Naïve
  • Experimental: Retifanlimab: Chemotherapy: Refractory

Primary Outcome Measure

Objective Response Rate (ORR) [ Time Frame: up to 26.8 months ]

Locations (16)

FacilityCityStateZIPSite coordinators
Stanford Cancer InstitutePalo AltoCalifornia94304-
University of California San Francisco Comprehensive Cancer CenterSan FranciscoCalifornia94143-
University of Colorado Cancer CenterAuroraColorado80045-
Georgetown University HospitalWashington D.C.District of Columbia20007-
Rush UniversityChicagoIllinois60612-
Norton Cancer InstituteLouisvilleKentucky40241-
Mayo Clinic RochesterRochesterMinnesota55905-
John Theurer Cancer Center, Hackensack University Medical CenterHackensackNew Jersey07601-
Rutgers Cancer Institute of NjNew BrunswickNew Jersey08901-
Roswell Park Cancer InstituteBuffaloNew York14263-
University of Rochester Medical CenterRochesterNew York14642-
The Christ HospitalCincinnatiOhio45219-
Upmc CancercenterPittsburghPennsylvania15232-
Inova Fairfax HospitalFairfaxVirginia22031-
University of Washington - Seattle Cancer Care AllianceSeattleWashington98109-
West Virginia University Hospitals IncMorgantownWest Virginia26506-

Find similar trials in Palo Alto, CA

By research site
Stanford Cancer Institute· Palo Alto, CAUniversity of California San Francisco Comprehensive Cancer Center· San Francisco, CAUniversity of Colorado Cancer Center· Aurora, COGeorgetown University Hospital· Washington D.C., DCRush University· Chicago, ILNorton Cancer Institute· Louisville, KY

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