A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America
- Sponsor
- Bayer
- Study ID
- NCT03470103
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321) — DRUGUse of intravitreal aflibercept in routine clinical practice in Latin America
Study Details
The main objectives of this observational cohort study are to describe the use of intravitreal aflibercept and to describe follow-up as well as treatment patterns in patients with wAMD or DME in routine clinical practice in Latin America for a study population of treatment naive patients and those who have received prior therapy (anti-VEGF injections, laser, steroids, etc.) and are being switched to intravitreal aflibercept injection.
Key Dates
- Start date
- Mar 28, 2018
- Status verified
- Jun 2021
- Primary completion
- Sep 21, 2020
- Completion
- Jan 15, 2021
Study Design
- Enrollment
- 643 participants (actual)
Arms
- Arm: Treatment naïve wAMDThe decision regarding treatment is made at the discretion of the attending physician, according to his/her medical practice
- Arm: Treatment naïve DMEThe decision regarding treatment is made at the discretion of the attending physician, according to his/her medical practice
- Arm: Previously treated wAMDThe decision regarding treatment is made at the discretion of the attending physician, according to his/her medical practice
- Arm: Previously treated DMEThe decision regarding treatment is made at the discretion of the attending physician, according to his/her medical practice
Primary Outcome Measure
Mean change of visual acuity as measured by ETDRS or Snellen chart [ Time Frame: At baseline and 12 months ]
Related Studies
- Stem Cell Ophthalmology Treatment Study IIRecruiting · MD Stem Cells · Westport, Connecticut
- Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein SodiumEARLY_PHASE1 · Recruiting · MediBeacon · Ann Arbor, Michigan
- Factors in Learning And Plasticity: Macular DegenerationRecruiting · University of Alabama at Birmingham · Birmingham, Alabama
- NYSCF Scientific Discovery BiobankRecruiting · New York Stem Cell Foundation Research Institute · New York, New York