Biospecimen Procurement for Head and Neck Disorders

Part of paid clinical trials in Washington D.C., District of Columbia.

Sponsor
National Cancer Institute (NCI)
Study ID
NCT03429036
Status
Recruiting
Apply to this trial

Conditions

  • Head and Neck Neoplasms
  • Hearing Disorder
  • Laryngeal Disease
  • Oral Mucosal Disease
  • Pharyngeal Neoplasm

Eligibility Criteria

Sex
ALL
Age
3 Years - 120 Years
Healthy Volunteers
Not accepted

Study Details

Background: Researchers want to learn more about head and neck disorders. Understanding these disorders could help them find better treatments. To do this, they are collecting tissue samples for research. Objective: To create a repository of tissue samples and data to better study conditions of the head and neck. Eligibility: People who had or will have tissue samples taken because of a head or neck disorder. They must be ages 3 and older and not pregnant to join Part 2. Design: Participants will be screened with a questionnaire, medical history, and physical exam. Part 1. Participants will give permission for any of their tissue samples leftover from private care or other research protocols to be used. If participants tissue did not contain normal tissue or if they have a condition that suggests a genetic issue, they will be invited to join Part 2. Part 2: Participants will have additional samples collected. These could be: * Blood: Blood is drawn through a needle in the arm. * Cheek swab or brushing: A cotton swab or small brush is rubbed inside the cheek. * Saliva: They rinse their mouth with water and spit into a tube or cup. * Skin biopsy: They are injected with a numbing drug. A biopsy tool removes a small piece of skin. * Mucosal biopsy: They are injected in the mouth with a numbing medication. A small piece of tissue from the inside of the cheek is removed. Participants samples will be used for future research, including genetic testing.

Key Dates

Start date
May 23, 2018
Status verified
Jun 2026
Primary completion
Jun 3, 2029
Completion
Dec 2, 2029

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: 1
    Subjects must be diagnosed with a disorder of the head and neck region

Primary Outcome Measure

To created a biorepository of diseased and normal tissue specimens for research purposes [ Time Frame: 06/03/2026 ]

Central Contacts

Locations (9)

FacilityCityStateZIPSite coordinators
George Washington University HospitalWashington D.C.District of Columbia20037
Richard Lush, Ph.D.
[email protected]
202-994-3647
Johns Hopkins Hospital Sibley Memorial HospitalWashington D.C.District of Columbia20016
Nyall London, M.D.
[email protected]
801-547-7851
MedStar Georgetown University HospitalWashington D.C.District of Columbia20007
Michael Hoa, M.D.
[email protected]
301-435-3455
Johns Hopkins Hospital BayviewBaltimoreMaryland21224
Nyall London, M.D.
[email protected]
801-547-7851
Johns Hopkins Hospital Broadway BaltimoreBaltimoreMaryland21205
Nyall London, M.D.
[email protected]
801-547-7851
Johns Hopkins Hospital GreenspringBaltimoreMaryland21287
Nyall London, M.D.
[email protected]
301-827-6933
Johns Hopkins Otolaryngology ClinicBethesdaMaryland20817
Nyall London, M.D.
[email protected]
801-547-7851
Johns Hopkins Suburban HospitalBethesdaMaryland20814
Nyall London, M.D.
[email protected]
801-547-7851
National Institutes of Health Clinical CenterBethesdaMaryland20892
National Cancer Institute Referral Office
[email protected]
888-624-1937

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George Washington University Hospital· Washington D.C., DCJohns Hopkins Hospital Sibley Memorial Hospital· Washington D.C., DCMedStar Georgetown University Hospital· Washington D.C., DCJohns Hopkins Hospital Bayview· Baltimore, MDJohns Hopkins Hospital Broadway Baltimore· Baltimore, MDJohns Hopkins Hospital Greenspring· Baltimore, MD

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