Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Northwestern University
Study ID
NCT03401762
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • MCI — BEHAVIORAL
    EMG-controlled game
  • Sham MCI — BEHAVIORAL
    Sham control game

Study Details

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations. This randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.

Key Dates

Start date
Jan 15, 2018
Status verified
Apr 2026
Primary completion
Apr 30, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
96 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Chronic stroke MCI Electromyogram (EMG) pairs
    Decoupling 2 muscles at a time with MCI
  • Experimental: Chronic stroke MCI EMG triplets
    Decoupling 3 muscles at a time with MCI
  • Experimental: Chronic stroke MCI while reaching
    Decoupling muscles with MCI while reaching to targets
  • Sham Comparator: Chronic stroke Sham MCI
    Sham control group
  • Experimental: Acute stroke MCI
    Decoupling muscles with MCI in acute stroke subjects
  • Sham Comparator: Acute stroke Sham MCI
    Acute stroke subjects sham comparator

Primary Outcome Measure

Wolf Motor Function Test [ Time Frame: baseline to 6 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Northwestern UniversityChicagoIllinois60611-

Find similar trials in Chicago, IL

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Northwestern University· Chicago, IL

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