Mechanistic Clinical Trial of Advanced Imaging for CRT

Part of paid clinical trials in Charlottesville, Virginia.

Sponsor
University of Virginia
Study ID
NCT03398369
Status
Recruiting
Apply to this trial

Conditions

  • Heart Failure, Systolic

Eligibility Criteria

Sex
ALL
Age
20 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

  • CMR/CTA Guidance for CRT — DIAGNOSTIC_TEST
    The intervention is the use of CMR and CTA to determine the optimal pacing site in the left ventricle for cardiac resynchronization therapy (CRT) and guide left ventricular lead placement.

Study Details

This is a mechanistic clinical trial with randomization to guidance for the CRT procedure using cardiac magnetic resonance (CMR) and computed tomography angiography (CTA) versus a standard procedure.

Key Dates

Start date
Jan 5, 2018
Status verified
Feb 2020
Primary completion
Jan 15, 2025
Completion
Jan 15, 2025

Study Design

Enrollment
180 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Intervention
    CMR-Guided CRT
  • No Intervention: Control
    Standard CRT

Primary Outcome Measure

Left ventricular end-systolic volume (LVESV) improvement [ Time Frame: One Year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Virginia Health SystemCharlottesvilleVirginia22908
John Hoover
[email protected]
434-243-4861

Find similar trials in Charlottesville, VA

By research site
University of Virginia Health System· Charlottesville, VA

Related Studies