Vinorelbine for Recurrent ACLC
- Sponsor
- Children's Cancer Group, China
- Study ID
- NCT03397953
- Phase
- PHASE2
- Status
- Completed
Conditions
- Anaplastic Large Cell Lymphoma
- Vinorelbine
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - 18 Years
- Healthy Volunteers
- Not accepted
Interventions
- Vinorelbine — DRUGVinorelbine will be used 25mg/m2/week, rest for 1 week after 3 weeks of continuous use, 4 weeks will be a course. After 1 week there will be a simple assessment, after 2 weeks will be a comprehensive assessment. If the patient got disease progression or partial response/stable disease, he/she would be removed from this trial.
Study Details
The purpose of this study is to assess the efficiency and safety of vinorelbine in the treatment of relapsed / advanced ALCL in children and adolescents.
Key Dates
- Start date
- Nov 30, 2016
- Status verified
- Jul 2022
- Primary completion
- Jul 31, 2022
- Completion
- Jul 31, 2022
Study Design
- Enrollment
- 20 participants (estimated)
- Allocation
- NON_RANDOMIZED
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Vinorelbine monotherapy treatmentPatients will be treated by Vinorelbine. Four weeks as a course. There are 20 courses in total.
Primary Outcome Measure
Event free survival [ Time Frame: 5 years ]
Related Studies
- Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological MalignanciesPHASE2 · Recruiting · Fred Hutchinson Cancer Center · Seattle, Washington
- Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell LymphomaPHASE1 · Recruiting · Mayo Clinic · Scottsdale, Arizona
- A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)PHASE1 · Recruiting · Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey
- A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)PHASE1 · Recruiting · National Cancer Institute (NCI) · Bethesda, Maryland